High-dose nitrate supplement attenuates the effects of isometric blood flow restriction exercise on blood pressure in healthy males, according to the recent study by researchers of the Northumbria University (UK), University of West Bohemia (Czech Republic), Ankara University (Turkey).
The findings of the research, published in the Nutrients journal, reveal that short-term high-dose NO3− supplementation elevated plasma NO2− concentration and reduced BP during a short isometric contraction and a sustained ischaemic contraction in healthy males. These findings support that NO3− supplementation is an effective nutritional intervention in reducing systolic blood pressure SBP and MAP in healthy young males during submaximal exercise.
The findings reveal that short-term high-dose NO3− supplementation elevated plasma NO2− concentration and reduced BP during a short isometric contraction and a sustained ischaemic contraction in healthy males. These findings support that NO3− supplementation is an effective nutritional intervention in reducing SBP and MAP in healthy young males during submaximal exercise.
Several important points must be considered when interpreting the findings of this study. The current investigation did not include females. However, since different plasma NO3− and BP responses between males and females have been reported, the findings of the present study can only be interpreted for males, and future studies should include females to investigate if the potential effect of NO3− supplementation in altering BP is different compared with males, and to what extent.
